diff --git a/telegram/request/_httpxrequest.py b/telegram/request/_httpxrequest.py
index 8c9c2f9ac..41cc8b21d 100644
--- a/telegram/request/_httpxrequest.py
+++ b/telegram/request/_httpxrequest.py
@@ -201,6 +201,9 @@ class HTTPXRequest(BaseRequest):
         except httpx.HTTPError as err:
             # HTTPError must come last as its the base httpx exception class
             # TODO p4: do something smart here; for now just raise NetworkError
-            raise NetworkError(f"httpx HTTPError: {err}") from err
+
+            # We include the class name for easier debugging. Especially useful if the error
+            # message of `err` is empty.
+            raise NetworkError(f"httpx.{err.__class__.__name__}: {err}") from err
 
         return res.status_code, res.content
diff --git a/tests/test_request.py b/tests/test_request.py
index 3a1659245..af074f842 100644
--- a/tests/test_request.py
+++ b/tests/test_request.py
@@ -533,18 +533,21 @@ class TestHTTPXRequest:
         assert content == b"content"
 
     @pytest.mark.parametrize(
-        ["raised_class", "expected_class"],
-        [(httpx.TimeoutException, TimedOut), (httpx.HTTPError, NetworkError)],
+        ["raised_class", "expected_class", "expected_message"],
+        [
+            (httpx.TimeoutException, TimedOut, "Timed out"),
+            (httpx.ReadError, NetworkError, "httpx.ReadError: message"),
+        ],
     )
     async def test_do_request_exceptions(
-        self, monkeypatch, httpx_request, raised_class, expected_class
+        self, monkeypatch, httpx_request, raised_class, expected_class, expected_message
     ):
         async def make_assertion(self, method, url, headers, timeout, files, data):
             raise raised_class("message")
 
         monkeypatch.setattr(httpx.AsyncClient, "request", make_assertion)
 
-        with pytest.raises(expected_class):
+        with pytest.raises(expected_class, match=expected_message):
             await httpx_request.do_request(
                 "method",
                 "url",