diff --git a/telegram/constants.py b/telegram/constants.py
index b3f4e9c5c..3c594fbe2 100644
--- a/telegram/constants.py
+++ b/telegram/constants.py
@@ -66,6 +66,7 @@ __all__ = [
     "UpdateType",
 ]
 
+import sys
 from typing import List, NamedTuple
 
 from telegram._utils.enum import IntEnum, StringEnum
@@ -334,6 +335,13 @@ class FileSizeLimit(IntEnum):
     """:obj:`int`: Bots can download files of up to 20MB in size."""
     FILESIZE_UPLOAD = int(50e6)  # (50MB)
     """:obj:`int`: Bots can upload non-photo files of up to 50MB in size."""
+    FILESIZE_UPLOAD_LOCAL_MODE = int(2e9)  # (2000MB)
+    """:obj:`int`: Bots can upload non-photo files of up to 2000MB in size when using a local bot
+       API server.
+    """
+    FILESIZE_DOWNLOAD_LOCAL_MODE = sys.maxsize
+    """:obj:`int`: Bots can download files without a size limit when using a local bot API server.
+    """
     PHOTOSIZE_UPLOAD = int(10e6)  # (10MB)
     """:obj:`int`: Bots can upload photo files of up to 10MB in size."""
 
diff --git a/tests/test_constants.py b/tests/test_constants.py
index c006bbd04..f6b004b2a 100644
--- a/tests/test_constants.py
+++ b/tests/test_constants.py
@@ -49,6 +49,7 @@ class TestConstants:
                 not key.startswith("_")
                 # exclude imported stuff
                 and getattr(member, "__module__", "telegram.constants") == "telegram.constants"
+                and key != "sys"
             )
         }
         actual = set(constants.__all__)