.. tip:: When combining ``python-telegram-bot`` with other :mod:`asyncio` based frameworks, using this method is likely not the best choice, as it blocks the event loop until it receives a stop signal as described above. Instead, you can manually call the methods listed below to start and shut down the application and the :attr:`~telegram.ext.Application.updater`. Keeping the event loop running and listening for a stop signal is then up to you.