diff --git a/crates/teloxide-core/schema.ron b/crates/teloxide-core/schema.ron
index 7d6ff142..5b382979 100644
--- a/crates/teloxide-core/schema.ron
+++ b/crates/teloxide-core/schema.ron
@@ -1851,6 +1851,37 @@ Schema(
                 ),
             ],
         ),
+        Method(
+            names: ("setMessageReaction", "SetMessageReaction", "set_message_reaction"),
+            return_ty: True,
+            doc: Doc(
+                md: "Use this method to change the chosen reactions on a message. Service messages can't be reacted to. Automatically forwarded messages from a channel to its discussion group have the same available reactions as messages in the channel. Returns True on success."
+            ),
+            tg_doc: "https://core.telegram.org/bots/api#setmessagereaction",
+            tg_category: "Available methods",
+            params: [
+                Param(
+                    name: "chat_id",
+                    ty: RawTy("Recipient"),
+                    descr: Doc(md: "Unique identifier for the target chat or username of the target channel (in the format @channelusername)")
+                ),
+                Param(
+                    name: "message_id",
+                    ty: RawTy("MessageId"),
+                    descr: Doc(md: "Identifier of the target message. If the message belongs to a media group, the reaction is set to the first non-deleted message in the group instead.")
+                ),
+                Param(
+                    name: "reaction",
+                    ty: Option(ArrayOf(RawTy("ReactionType"))),
+                    descr: Doc(md: "New list of reaction types to set on the message. Currently, as non-premium users, bots can set up to one reaction per message. A custom emoji reaction can be used if it is either already present on the message or explicitly allowed by chat administrators.")
+                ),
+                Param(
+                    name: "is_big",
+                    ty: Option(bool),
+                    descr: Doc(md: "Pass True to set the reaction with a big animation")
+                ),
+            ],
+        ),
         Method(
             names: ("getUserProfilePhotos", "GetUserProfilePhotos", "get_user_profile_photos"),
             return_ty: RawTy("UserProfilePhotos"),
diff --git a/crates/teloxide-core/src/adaptors/cache_me.rs b/crates/teloxide-core/src/adaptors/cache_me.rs
index caab3f87..4ab96541 100644
--- a/crates/teloxide-core/src/adaptors/cache_me.rs
+++ b/crates/teloxide-core/src/adaptors/cache_me.rs
@@ -116,6 +116,7 @@ where
         send_poll,
         send_dice,
         send_chat_action,
+        set_message_reaction,
         get_user_profile_photos,
         get_file,
         kick_chat_member,
diff --git a/crates/teloxide-core/src/adaptors/erased.rs b/crates/teloxide-core/src/adaptors/erased.rs
index 1e3ca58b..0c2a907d 100644
--- a/crates/teloxide-core/src/adaptors/erased.rs
+++ b/crates/teloxide-core/src/adaptors/erased.rs
@@ -215,6 +215,7 @@ where
         send_poll,
         send_dice,
         send_chat_action,
+        set_message_reaction,
         get_user_profile_photos,
         get_file,
         kick_chat_member,
@@ -480,6 +481,12 @@ trait ErasableRequester<'a> {
         action: ChatAction,
     ) -> ErasedRequest<'a, SendChatAction, Self::Err>;
 
+    fn set_message_reaction(
+        &self,
+        chat_id: Recipient,
+        message_id: MessageId,
+    ) -> ErasedRequest<'a, SetMessageReaction, Self::Err>;
+
     fn get_user_profile_photos(
         &self,
         user_id: UserId,
@@ -1222,6 +1229,14 @@ where
         Requester::send_chat_action(self, chat_id, action).erase()
     }
 
+    fn set_message_reaction(
+        &self,
+        chat_id: Recipient,
+        message_id: MessageId,
+    ) -> ErasedRequest<'a, SetMessageReaction, Self::Err> {
+        Requester::set_message_reaction(self, chat_id, message_id).erase()
+    }
+
     fn get_user_profile_photos(
         &self,
         user_id: UserId,
diff --git a/crates/teloxide-core/src/adaptors/parse_mode.rs b/crates/teloxide-core/src/adaptors/parse_mode.rs
index f9458bca..1b4fba80 100644
--- a/crates/teloxide-core/src/adaptors/parse_mode.rs
+++ b/crates/teloxide-core/src/adaptors/parse_mode.rs
@@ -197,6 +197,7 @@ where
         send_contact,
         send_dice,
         send_chat_action,
+        set_message_reaction,
         get_user_profile_photos,
         get_file,
         kick_chat_member,
diff --git a/crates/teloxide-core/src/adaptors/throttle/requester_impl.rs b/crates/teloxide-core/src/adaptors/throttle/requester_impl.rs
index eb9cbb41..0fbe3a5f 100644
--- a/crates/teloxide-core/src/adaptors/throttle/requester_impl.rs
+++ b/crates/teloxide-core/src/adaptors/throttle/requester_impl.rs
@@ -99,6 +99,7 @@ where
         stop_message_live_location,
         stop_message_live_location_inline,
         send_chat_action,
+        set_message_reaction,
         get_user_profile_photos,
         get_file,
         kick_chat_member,
diff --git a/crates/teloxide-core/src/adaptors/trace.rs b/crates/teloxide-core/src/adaptors/trace.rs
index cef5fa7e..7c6ebfa8 100644
--- a/crates/teloxide-core/src/adaptors/trace.rs
+++ b/crates/teloxide-core/src/adaptors/trace.rs
@@ -145,6 +145,7 @@ where
         send_poll,
         send_dice,
         send_chat_action,
+        set_message_reaction,
         get_user_profile_photos,
         get_file,
         kick_chat_member,
diff --git a/crates/teloxide-core/src/bot/api.rs b/crates/teloxide-core/src/bot/api.rs
index 7da6ee98..27912b41 100644
--- a/crates/teloxide-core/src/bot/api.rs
+++ b/crates/teloxide-core/src/bot/api.rs
@@ -309,6 +309,18 @@ impl Requester for Bot {
         Self::SendChatAction::new(self.clone(), payloads::SendChatAction::new(chat_id, action))
     }
 
+    type SetMessageReaction = JsonRequest<payloads::SetMessageReaction>;
+
+    fn set_message_reaction<C>(&self, chat_id: C, message_id: MessageId) -> Self::SetMessageReaction
+    where
+        C: Into<Recipient>,
+    {
+        Self::SetMessageReaction::new(
+            self.clone(),
+            payloads::SetMessageReaction::new(chat_id, message_id),
+        )
+    }
+
     type GetUserProfilePhotos = JsonRequest<payloads::GetUserProfilePhotos>;
 
     fn get_user_profile_photos(&self, user_id: UserId) -> Self::GetUserProfilePhotos {
diff --git a/crates/teloxide-core/src/local_macros.rs b/crates/teloxide-core/src/local_macros.rs
index 41ae27a6..242f807b 100644
--- a/crates/teloxide-core/src/local_macros.rs
+++ b/crates/teloxide-core/src/local_macros.rs
@@ -667,6 +667,14 @@ macro_rules! requester_forward {
             $body!(send_chat_action this (chat_id: C, action: ChatAction))
         }
     };
+    (@method set_message_reaction $body:ident $ty:ident) => {
+        type SetMessageReaction = $ty![SetMessageReaction];
+
+        fn set_message_reaction<C>(&self, chat_id: C, message_id: MessageId) -> Self::SetMessageReaction where C: Into<Recipient> {
+            let this = self;
+            $body!(set_message_reaction this (chat_id: C, message_id: MessageId))
+        }
+    };
     (@method get_user_profile_photos $body:ident $ty:ident) => {
         type GetUserProfilePhotos = $ty![GetUserProfilePhotos];
 
diff --git a/crates/teloxide-core/src/payloads.rs b/crates/teloxide-core/src/payloads.rs
index ee3f845e..cdcd85f1 100644
--- a/crates/teloxide-core/src/payloads.rs
+++ b/crates/teloxide-core/src/payloads.rs
@@ -117,6 +117,7 @@ mod set_chat_title;
 mod set_custom_emoji_sticker_set_thumbnail;
 mod set_game_score;
 mod set_game_score_inline;
+mod set_message_reaction;
 mod set_my_commands;
 mod set_my_default_administrator_rights;
 mod set_my_description;
@@ -256,6 +257,7 @@ pub use set_custom_emoji_sticker_set_thumbnail::{
 };
 pub use set_game_score::{SetGameScore, SetGameScoreSetters};
 pub use set_game_score_inline::{SetGameScoreInline, SetGameScoreInlineSetters};
+pub use set_message_reaction::{SetMessageReaction, SetMessageReactionSetters};
 pub use set_my_commands::{SetMyCommands, SetMyCommandsSetters};
 pub use set_my_default_administrator_rights::{
     SetMyDefaultAdministratorRights, SetMyDefaultAdministratorRightsSetters,
diff --git a/crates/teloxide-core/src/payloads/set_message_reaction.rs b/crates/teloxide-core/src/payloads/set_message_reaction.rs
new file mode 100644
index 00000000..834336ba
--- /dev/null
+++ b/crates/teloxide-core/src/payloads/set_message_reaction.rs
@@ -0,0 +1,25 @@
+//! Generated by `codegen_payloads`, do not edit by hand.
+
+use serde::Serialize;
+
+use crate::types::{MessageId, ReactionType, Recipient, True};
+
+impl_payload! {
+    /// Use this method to change the chosen reactions on a message. Service messages can't be reacted to. Automatically forwarded messages from a channel to its discussion group have the same available reactions as messages in the channel. Returns True on success.
+    #[derive(Debug, PartialEq, Eq, Hash, Clone, Serialize)]
+    pub SetMessageReaction (SetMessageReactionSetters) => True {
+        required {
+            /// Unique identifier for the target chat or username of the target channel (in the format @channelusername)
+            pub chat_id: Recipient [into],
+            /// Identifier of the target message. If the message belongs to a media group, the reaction is set to the first non-deleted message in the group instead.
+            #[serde(flatten)]
+            pub message_id: MessageId,
+        }
+        optional {
+            /// New list of reaction types to set on the message. Currently, as non-premium users, bots can set up to one reaction per message. A custom emoji reaction can be used if it is either already present on the message or explicitly allowed by chat administrators.
+            pub reaction: Vec<ReactionType> [collect],
+            /// Pass True to set the reaction with a big animation
+            pub is_big: bool,
+        }
+    }
+}
diff --git a/crates/teloxide-core/src/payloads/setters.rs b/crates/teloxide-core/src/payloads/setters.rs
index 96ba6712..279fda1d 100644
--- a/crates/teloxide-core/src/payloads/setters.rs
+++ b/crates/teloxide-core/src/payloads/setters.rs
@@ -39,7 +39,7 @@ pub use crate::payloads::{
     SetChatMenuButtonSetters as _, SetChatPermissionsSetters as _, SetChatPhotoSetters as _,
     SetChatStickerSetSetters as _, SetChatTitleSetters as _,
     SetCustomEmojiStickerSetThumbnailSetters as _, SetGameScoreInlineSetters as _,
-    SetGameScoreSetters as _, SetMyCommandsSetters as _,
+    SetGameScoreSetters as _, SetMessageReactionSetters as _, SetMyCommandsSetters as _,
     SetMyDefaultAdministratorRightsSetters as _, SetMyDescriptionSetters as _,
     SetMyNameSetters as _, SetMyShortDescriptionSetters as _, SetPassportDataErrorsSetters as _,
     SetStickerEmojiListSetters as _, SetStickerKeywordsSetters as _,
diff --git a/crates/teloxide-core/src/requests/requester.rs b/crates/teloxide-core/src/requests/requester.rs
index 0b97abf9..2936e8b2 100644
--- a/crates/teloxide-core/src/requests/requester.rs
+++ b/crates/teloxide-core/src/requests/requester.rs
@@ -413,6 +413,17 @@ pub trait Requester {
     where
         C: Into<Recipient>;
 
+    type SetMessageReaction: Request<Payload = SetMessageReaction, Err = Self::Err>;
+
+    /// For Telegram documentation see [`SetMessageReaction`].
+    fn set_message_reaction<C>(
+        &self,
+        chat_id: C,
+        message_id: MessageId,
+    ) -> Self::SetMessageReaction
+    where
+        C: Into<Recipient>;
+
     type GetUserProfilePhotos: Request<Payload = GetUserProfilePhotos, Err = Self::Err>;
 
     /// For Telegram documentation see [`GetUserProfilePhotos`].
@@ -1307,6 +1318,7 @@ macro_rules! forward_all {
             send_poll,
             send_dice,
             send_chat_action,
+            set_message_reaction,
             get_user_profile_photos,
             get_file,
             kick_chat_member,